
Ray Alvarez
Life Science Researcher & Entreprenuer
A Bit About Me.
I am a biotech entrepreneur with over 15 years of experience in drug development, specializing in immunology, virology, and biotechnology. I co-founded Ichor Biologics, where we developed a novel platform for monoclonal antibody discovery for infectious diseases, and as Co-Founder and Director of Immunobiology at Imprint Labs, I focus on advancing experimental immune profiling tools to define the etiology of autoimmune diseases. I’m driven by a passion for transforming scientific discoveries into impactful therapies, fostering collaborative teams, and leading innovative projects that improve patient outcomes.

Work Experience
Imprint Labs
Co-founder | Director of ImmunoBiology
Nov. 2023 - Present
Icahn School of Medicine at Mt. Sinai
Assistant Professor
Jan. 2017- Nov. 2023
Ichor Biologics
Co-founder | CEO
Jan 2014 - Present
Icahn School of Medicine at Mt. Sinai
Post-Doctoral Fellow/Instructor
June. 2010- Dec. 2016
At Imprint Labs, I lead research initiatives focused on developing cutting-edge immune profiling tools to accelerate personalized diagnostics and therapeutics for autoimmune diseases. Our mission is to decode complex immune histories and gain insights into autoimmunity, enabling faster and more accurate identification of disease mechanisms and therapeutic targets.
My academic research focused on understanding immune responses to viral infections, specifically characterizing HIV-1 and SARS-CoV-2 pathogenesis, as well as antibody-mediated immune responses. For these studies, I developed and optimized several novel assays to investigate neutralizing and non-neutralizing antibody-mediated effector responses (e.g., ADCC) and the immune mechanisms that contribute to viral control in chronic infections.
As Co-Founder and CEO of Ichor Biologics, I led the development of a novel platform to produce human monoclonal antibodies for treating infectious diseases. Our innovative platform isolates high-affinity, pathogen-specific antibodies derived from convalescent patients, aiming to accelerate therapeutic development and provide safe, clinically effective treatments for global health challenges.
My post-doctoral research focused on characterizing the mechanisms of HIV-1 cell-cell transmission. I spearheaded a seminal study that uncovered how HIV-1 Vpu antagonism of the host restriction factor tetherin impairs antibody-dependent cellular cytotoxicity (ADCC), revealing a novel immune evasion mechanism and linking tetherin expression to enhanced NK cell-mediated clearance of infected cells. These findings were highlighted in Nature Reviews Microbiology.
Education
2005 - 2009
Ph.D., Molecular Virology/Immunology
King’s College London, London, UK
Thesis: Ps20, a novel secreted factor that promotes HIV-1 infection in memory CD4+ T-cells
PhD supervisors: Anna Vyakarnam PhD, Mike Malim PhD
2002 - 2003
M.Sc., Immunology of Infectious Diseases
The London School of Hygiene & Tropical Medicine, London, UK
Thesis: Examining the gene expression correlates of Memory CD4+ T cells with the differential susceptibility to HIV-1 infection.
Thesis supervisors: Anna Vyakarnam PhD
1996 – 2000
B.S., Molecular Biology/Biochemistry & Philosophy (Dual Degree)​
Boston University, Boston, MA